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Old 01-17-2011, 06:22 AM
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Default Clenbuterol

Clenbuterol

Characteristics:
Clenbuterol is a very widely used drug and has quite a reputation. A good one among athletes and recreational users, and a very bad one among those people who know very little about illegal performance enhancing aids. Its not a steroid. In fact, the only medical use for which clenbuterol is generally prescribed (and now being less and less prescribed thanks to its illegitimate use) is for obstructions of the air-way. People with chronic breathing disorders like asthma use this as a bronchodilator to make breathing easier. But its only one of the many things that can be achieved with the use of clenbuterol.
In terms of action this drug is best likened to the now also illegal ephedrine and its legal replacement, ma huang. All of them operate mainly by increasing the manufacture and secretion of catabolic hormones known as cathecholamines (like dopamine, epinephrine (adrenaline) and norepinephrine (noradrenaline)) which are secreted from the adrenal region. Now these hormones have a wide variety of functions. First of all they seem to alter the contractile characteristics of smooth muscle, but very specifically. Some will apparently be stimulated, and others inhibited. Amongst those inhibited, the smooth muscles in the bronchial tree, which explains its soothing effect in patients with breathing problems. What it also does is increase thermogenisis. This usually encompasses a rise in blood pressure, a stimulatory effect of the heart muscle and a resulting rise in body temperature.
Along with the reversing of the effects of insulin (and inhibiting the action of insulin) which results in a release of glycogen back into the blood stream as glucose and an inability to store or use more glycogen, it will increase the rate of protein and fat being burned in the body. For bodybuilders that appears to be the primary use of the drug. This thermogenisis and an increase in the rate of fat being burned usually has as a result that the metabolic rate of the subject its much higher and he burns more calories. This in turn results in loss of adipose tissue (the shedding of fat in other words) revealing a leaner physique with cuts and striations. The downside to this effect is that there is a concomitant rise in the rate of protein being burned. Where fat is robbed from the fatty tissue in the body, protein is generally robbed from the muscle. As with all catabolic hormones, in time muscle loss can and will occur. Which is why many opt to use this compound during a cycle of anabolic steroids that will help preserve the lean body mass while reducing the fat.
Among the other actions that cathecholamines have is an increase in aerobic capacity (facilitated by the easier breathing), a stimulation of the nervous system (facilitated by norepinephrine and acetylcholine release) and thus the skeletal muscle system, an increase in oxygen transportation (facilitated by the increased blood pressure) and an increase in vigil. These characteristics in turn combine to make this drug particularly interesting for athletes doing endurance sports and needing a boost. Especially in middle-long running numbers, this drug is widely abused and its no secret that in cycling circles clenbuterol in liquid form is combined with a painkiller and the drug EPO (synthetic erythropoeitin, a renal hormone) which increases the manufacture of red blood cells. It is then injected along the road, thereby avoiding positive tests prior to the race. Needless to say such a cocktail is very hazardous to the cardiovascular system. Just to demonstrate the wide use of this drug and its immense popularity among athletes, observe the US Olympic team. Exercise-induced asthma is an afflmiction that generally occurs in 3-7% of the population, and is in some rare cases treated with clenbuterol. In 2000 60% of US Olympic athletes claimed to have exercise-induced asthma and ALL of them were prescribed clenbuterol for this condition. An otherwise illegal drug, tolerated solely for this reason. And this while the Romanian gymnast Andrea Raducan was stripped of her gold medal for the 25 g of norephedrine in her cold medicin she was taking...
In several animal studies1,2,3 Clenbuterol was also shown to act as an anabolic, believed to be able to impart muscle gains. This was never demonstrated in humans4 however, and there is more evidence that its effect on catabolic hormones invokes the opposite. In any case, the animal studies used much higher doses5 then one would safely recommend for humans. The late Dan Duchaine, by many held in high regard as a steroid guru and a former writer of the now defunct MM2K, believed it had something to do with the stimulation of a third beta receptor, which was different in humans as opposed to other mammals, and that this was the reason humans did not receive any anabolic benefits. As with most of what Dan said, this is very questionable, but one of many possible explanations in a debate that still rages on. Despite the many claims of other bodybuilders that still swear it has some form of anabolic action, I must say I've seen enough proof to the contrary to strongly advise against buying clenbuterol for promoting muscle mass. You may be more than sorely disappointed. Next time you see a 230 pound, 6 foot top-level cyclist, let me know and I may change my mind.
Clenbuterol, when used for its fat-burning properties is best used in a pyramid scheme. Slowly building up the dose may be more important that tapering off of it, as most first time users will rarely if ever know how they will react. Because of the effects on blood pressure its best to start with 20-40 g per day and slowly work your way up increasing the dose every 3 days by 20 g, to a maximum of 120-160 g (most find 80 g to be adequate). Its also best not used for long periods of time. Body homeostasis seems to negate the excitatory and inhibitive functions of clenbuterol over time, creating a complacency effect. It loses most of its nerve stimulation and fat burning benefits after 3-4 weeks, and using it longer on end would be futile. The user is best to discontinue use for an equal period of time and then recommence again.
Another thing people should be aware of is the inherent liver toxicity associated with clenbuterol use. When stacking with oral 17-alpha-alkylated steroids, accutane, anti-biotics or other hepatoxic elements, one should have his liver values checked by a licensed physician at regular points in time to avoid all problems. If you not a yellow discoloration of the skin cease use immediately and contact your doctor.

Stacking and Use:
Clenbuterol should be built up and tapered off gradually with dosage increases and decreases every 3-4 days and doses never exceeding 160 g per day to be perfectly safe. Its mostly used for periods of 2-3 weeks then discontinued for equal periods of time to disallow the body to adapt to the effects of the drug. For fat-burning goals clenbuterol is often stacked with another fat-burning agent for quick effect, or alternated with another fat-burning agent by people who need to stay lean on a year-round basis. Usually cytomel (T3) is used for such purposes, with alternating cycles of 3 weeks each. If used together, cycles will not completely overlap, but differ slightly so as not to match the low doses with the low and the high doses with the high. A typical cycle for clenbuterol might be 3 weeks, with the daily amounts being: 40/40/40/60/60/60/80/80/80/100/100/100/80/80/80/60/60/60/40/40/40 g/day.
Then stopping for three weeks and recommencing.
It's also commonly stacked with anabolic steroids. Usually non-aromatizing steroids that give the user a leaner and harder look, and allow for less water retention. They serve a main purpose of allowing the user to keep as much of his hard-earned muscle mass as he tries to shed the fat he has stocked up in the off-season with catabolic precursors such as clenbuterol. Clenbuterol is generally regarded as fairly safe6, hence its wide-spread use. It should be disadvised for all with blood pressure and/or previously diagnosed cardio-vascular problems. But most tolerate it quite well. By building up the dose over time they usually see when they've reached a dose that becomes too harsh. The use of clenbuterol will elicit higher body temperature, higher blood pressure and in some, especially at high doses, insomnia and jitters. Though these should not be nearly as pronounced with clenbuterol as they are with ephedrine and its legal counterpart ma huang. They are also easily remedied by shifting doses around so you don't take clenbuterol in the hours leading up to bedtime and most of it in pre-training phases when the drug can enhance your training vigor.
Another good match for clenbuterol in a stack is the plant derivative yohimbine Hcl. It does concern the standardized product yohimbine here and not the raw material yohimbe, which is useless. In small doses of 20-30 mg per day, it can stop the down-regulation of the noradrenaline feedback mechanisms, that usually inhibit the actions of noradrenaline by reducing receptor affinity. This has two important uses. The first is that the length of action of clenbuterol can be enhanced by a few hours when using it together with yohimbine Hcl (although it already has a considerable half-life time7 of 36 hours and one daily dose should suffice) , and the second is that concomitant use of yohimbine Hcl may allow clenbuterol to induce its fatburning aspects on a longer term than the normal 2-3 weeks, so it can be used for 5-6 weeks instead. Yohimbine Hcl is, at least for now still, a legal supplement that can be acquired for very little money from legal sources and supplement companies.
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Old 01-17-2011, 06:24 AM
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Clenbuterol FAQ: Everything you need to know about Clen
I wrote this because of all the confusion that surrounds this drug. Enjoy.

What is Clenbuterol?
Clenbuterol is a beta-2 agonist and is used in many countries as a broncodilator for the treatment of asthma. Because of it's long half life, clenbuterol is not FDA approved for medical use. It is a central nervous system stimulant and acts like adrenaline. It shares many of the same side effects as other CNS stimulants like ephedrine. Contrary to popular belief, Clenbuterol has a half life of 35 hours and not 48 hours.

Dosing and Cycling
Clenbuterol comes in 20mcg tablets, although it is also available in syrup, pump and injectable form. Doses are very dependent on how well the user responds to the side effects, but somewhere in the range of 5-8 tablets per day for men and 1-4 tablets a day for women is most common. Clenbuterol loses its thermogenic effects after 6-8 weeks when body temperature drops back to normal. It's anabolic/anti-catabolic properties fade away at around the 18 day mark. Taking the long half life into consideration, the most effective way of cycling clen is 2 weeks on/ 2 weeks off for no more than 12 weeks. Ephedrine can be used in the off weeks.

Clenbuterol vs Ephedrine vs DNP
Ephedrine will raise metabolic levels by about 2-3 percent and 200mg of DNP raises metabolic levels by about 30 percent. Clenbuterol raises metabolic levels about 10 percent and it can raise body temperature several degrees.

DNP is by far the most effective fat burner but many people will never use it because of the risks associated with it. It also offers no anti-catabolic benefit. Although it does have anti-catabolic effect, ephedrine short half life prevents it from being all that effective.

As far as side effects, Clenbuterol's are certainly milder than DNP's, and some would even say milder than an ECA stack. There is no ECA-style crash on Clenbuterol and many users find it easier on the prostate and sex drive. This may in part be due to the fact that Clen is generally used for only 2 weeks at a time.

Side effects

NAUSEA
NERVOUSNESS
DIZZINESS
DROWSINESS
DRY MOUTH
FACIAL FLUSHING
HEADACHE
HEARTBURN
INCREASED BLOOD PRESSURE
INCREASED SWEATING
INSOMNIA
LIGHTHEADEDNESS
MUSCLE CRAMPS
TREMORS
VOMITING
CHEST PAIN

The most significant side effects are muscle cramps, nervousness, headaches, and increased blood pressure.

Muscle cramps can be avoided by drinking 1.5-2 gallons of water and consuming bananas and oranges or supplementing with GNC potassium tablets at 200-400mg a day taken before bed on an empty stomach.

Headaches can easily be avoided with Tylenol Extra Strength taken at the first signs of a headache. You may need to take double the recommended dose.

Common Uses
Post-Cycle Therapy: Clen is used post cycle to aid in recovery. It allows the user to continue eating large amounts of food, without worrying about adding body fat. It also helps the user maintain more of his strength as well as his intensity in the gym. Diet: Roughly the same as on cycle.

Fat loss: The most popular use for Clen, it also increases muscle hardness, vascularity, strength and size on a caloric deficit. For the most significant fat loss, Clen can be stacked with T3. Diet: A high protein(1.5g per lb of bodyweight), moderate carb(0.5g to 1g per lb of bodyweight), low fat diet(0.25g per lb of bodyweight) seems to work best with Clen.

Alternative to Steroids: Clenbuterol has mild steroid-like properties and can be used by non AS using bodybuilder to increase LBM as well as strength and muscle hardness. Diet: A moderate carb, high protein, moderate fat diet work well.

Stimulant/Performance Enhancement: It can be used as a stimulant, but an ECA stack may be a better choice because of it's much shorter half-life. Diet: To take full advantage of the stimulatory effects of Clen, Carbs must be included in the diet. Keto diet do not work well in this case.

Precautions: Is Clen for you?
The same precautions that apply to Ephedrine must be applied to Clen, although some people find ECA stacks harsher than Clen. It should not be stacked with other CNS stimulants such as Ephedrine and Yohimbine. These combinations are unnecessary and potentially dangerous. Caffeine can be used in moderation before a workout for an extra kick, although its diuretic effects may shift electrolyte balance. Drink more water if you use Caffeine.

What else do I need to know?
Most users that report bad side effects and discontinue use are those who use high doses right at the start of the cycle. The worst side effects occur within the first 3-4 days of use.

A first time user should not exceed 40mcg the first day.

Example of a first cycle:
Day1: 20mcg
Day2: 40mcg
Day3: 60mcg
Day4: 80mcg
Day5: 80mcg(Note: Increase the dose only when the side effects are tolerable)
Day6-Day12: 100mcg
Day13: 80mcg (Tapering is not necessary, but it helps some users get back to normal gradually)
Day14: 60mcg
Day15: off
Day16: off
Day 17: ECA/ NYC stack

Example of a second cycle:
Day1: 60mcg
Day2: 80mcg
Day3: 80mcg
Day4: 100mcg
Day5: 100mcg
Day6-Day12: 120mcg
Day13: 100mcg
Day14: 80mcg
Day15: off
Day16: off
Day 17: ECA/ NYC stack

Do not take Clen Past 4pm and drink plenty of water: 1.5-2 gallons a day.

All brands are not equal when it comes to Clen, different brands will yield different results.
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Old 10-06-2012, 12:39 PM
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Hey cc. Dumb question but do i spread the dose out through the day or take it all at once.
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Old 10-06-2012, 01:09 PM
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A lot of debate on that one, Personally I spread it throughout the day(this is also what I recommend)
However I do know a lot of guys who take it all in one go
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Old 10-06-2012, 01:29 PM
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Sounds good. Im only going to run it for two weeks to cap off my cut. Getting them bottom two abs to pop is always a bitch. Hopefully clen will make it easier
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Old 10-07-2012, 12:52 AM
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I agree with CC spread it out. Atleat that way you can see how you feel during the day. I think it is alot safer aswell.
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Old 10-08-2012, 05:36 PM
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Hey CC,

I bought some Kalpa Clen for my wife and Im trying to lay out her daily dosage. This will be her first time taking clen. Can you recommend a typical dosage chart for women? Of coarse I will be monitoring her daily dosage and will alter to meet her needs but I just wanted to see what your thoughts might be. She is currently 5'4 @ 120lbs. She is a runner and wants to tone up and shed some unwanted body fat, which isn't much. Any opinions or thoughts would be appreciated.
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Old 10-08-2012, 06:11 PM
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I would say start her off on half a tab per day for 2 or 3 days and see how it goes then possibly up the dosage to 40mcg(1 tab) and again see how it goes, woman respond to much lower doses than men so take it slowly
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Old 10-08-2012, 08:11 PM
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Thanks for fast response. I will try that and see how it goes, Thanks
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Old 08-30-2015, 07:14 PM
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I will be a first time user of clen. as a first time user i made the mistake of getting it in liquid form. how would i dose it in liquid?
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