Thread: Peptide Guide
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Old 12-05-2022, 05:59 PM
01dragonslayer 01dragonslayer is offline
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HGH Fragment 176-191
HGH Fragment 176-191 is a fragment of the HGH peptide. Scientists found that if they truncated the peptide at the C terminal region they could isolate the fat loss attributes associated with HGH. Taking this fragment from HGH, including the peptide bonds from 176-191, they found they had developed a peptide that regulated fat loss 12.5 times better than regular HGH. It has an incredibly ability to regulate fat metabolism without the adverse side effects on insulin sensitivity. By isolating the tail end of the GH molecule, scientists have found that HGH Frag 176-191 works even better than HGH to stimulate lipolysis (breaking down of fat). In fact, it actually inhibits lipogenesis; meaning, it stops formation of fatty acids and other lipids. Also, unlike other fat burning compounds out there, users will not experience hunger suppressing qualities or the jittery feelings that can be associated with ephedrine like compounds. Since it does not compete for HGH receptors, multiple studies have shown that HGH Frag 176-191 will not cause hyperglycemia. In addition, it will promote lean body mass, protein synthesis, increase bone mineral density, and better sleep.

IGF1-DES
IGF-1 DES is a peptide secreted by the liver and consists of 67 amino acids. IGF-1 DES stimulates hormones as it is a highly anabolic structure. In living organisms, IGF-1 DES offers a number of benefits and is responsible for creating hyperplasia (or hypergensis), which is a process that regulates the growth of cells. Scientific research involving IGF-1 DES indicates the peptide is also capable of influencing neurological growth, maintain nerve cell function, and promote nerve growth. Its ability to create hyperplasia leads scientists to use animals for researching the ability of IGF-1 DES in relation to growing cells and the development of tissue. Studies show that IGF-1 DES has the capability to influence the neuronal structure and functions of the brain, and continuing animal studies are watching the peptideís effects on muscular and skeletal growth.

IGF1-LR3
The polypeptide IGF-1 LR3, also known as Long R3 IGF-1, is a peptide chain consisting of 83 amino acids. It contains a molecular weight of 9200, and its molecular structure of C990H1528N262O300S7. Specifically, scientific studies have determined that IGF-LR3ís relationship with the pancreas and liver can be traced down to specific secretions. In the case of the pancreas, it has been determined that the peptide can be linked to the secretion of insulin. This secretion guides the cells that are found within the skeletal muscles, fatty tissues, and liver to absorb glucose from an animal test subjectís bloodstream. In the case of the liver, it has been determined that the peptide can be linked to the secretion of IGF-1, also known as Insulin-like Growth Factor-1 or Somatomedin C. This secretion has been shown to possess highly anabolic properties. What this means is, the secretion has been determined to play a vital role in muscle and tissue growth as it relates to muscular and skeletal tissue growth and repair.

Insulin
Insulin (/ˈɪn.sjʊ.lɪn/ from Latin insula, 'island') is a peptide hormone produced by beta cells of the pancreatic islets; it is considered to be the main anabolic hormone of the body. It regulates the metabolism of carbohydrates, fats and protein by promoting the absorption of glucose from the blood into liver, fat and skeletal muscle cells. In these tissues the absorbed glucose is converted into either glycogen via glycogenesis or fats (triglycerides) via lipogenesis, or, in the case of the liver, into both. Glucose production and secretion by the liver is strongly inhibited by high concentrations of insulin in the blood.

Circulating insulin affects the synthesis of proteins in a wide variety of tissues. It is therefore an anabolic hormone, promoting the conversion of small molecules in the blood into large molecules inside the cells. Low insulin levels in the blood have the opposite effect by promoting widespread catabolism, especially of reserve body fat. The secretion of insulin and glucagon into the blood in response to the blood glucose concentration is the primary mechanism of glucose homeostasis.

Ipamorelin
Ipamorelin is a pentipeptide, meaning that its structure is comprised of five amino acids. It contains a molecular mass of 711.85296, and its molecular formula is C38H49N9O5. It can sometimes go by the alternate names Ipamorelin Acetate, IPAM, and NNC-26-0161. It is a secretogogue, and is considered to be an agonist, meaning that it possesses the ability to bind certain receptors of a cell and provokes a cellular response. Ipamorelinís operational mechanics enables the peptide to stimulate the production of pituitary gland-based expression of secretions related to growth amongst animal test subjects. At the same time, the presence of the peptide has been shown to inhibit the production of a secretion known as somatostatin. In essence, this peptide is primarily responsible for inhibiting the production of growth secretions. Additionally, it has been determined that Ipamorelin has the ability to boost the production of IGF-1, or Insulin-like Growth Factor 1. This particular peptide, which is secreted by the liver, has been shown to be highly anabolic in its nature. What this means is, its presence plays a key role in the overall growth and repair of muscular and skeletal tissue.

MGF (Mechano Growth Factor)
Mechano Growth Factor (MGF) also known as IGF-1Ec is a growth factor/repair factor that is derived from exercised or damaged muscle tissue. What makes MGF special is its unique role in muscle growth. MGF has the ability to cause wasted tissue to grow and improve by activating muscle stem cells and increasing the up-regulation of protein synthesis, this unique ability can rapidly improve recovery and speed up muscle growth. MGF can initiate muscle satellite (stem) cell activation in addition to its IGF-1 receptor domain which, in turn, increases protein synthesis turnover; therefore, if used correctly it can improve muscle mass over time. MGF is like a highly anabolic variant of IGF. After you have trained, the IGF-I gene is spliced towards MGF then that causes hypertrophy and repair of local muscle damage by activating the muscle stem cells as well as other important anabolic processes, including the above mentioned protein synthesis, and increased nitrogen retention.

PEG-MGF
PEG-MGF is pegylated mechanic growth factor, which is a research peptide used in a variety of scientific research conducted throughout the world. The peptide has proved useful with the MGF being a variant of IGF (insulin-like growth factor), which is responsible for increasing the stem cell count in muscles. This enables the muscles fibers to mature and fuse. The peptide is being thoroughly tested in patients where muscle fibers are broken down and need assistance with muscle growth. The PEG-MGF peptide creates new fibers, promotes protein synthesis and helps with nitrogen retention; this makes it ideal for those who do hard workouts or suffer from muscular diseases.

PT-141 Bremelanotide
PT-141, also known as Bremelanotide, is a research peptide that has shown promise in scientific studies, on animal test subjects, to regulate blood flow restriction, inflammation, and helping improve sexual dysfunction. PT-141 was developed from the Melanotan 2 Peptide, which underwent studies in a laboratory setting as a sunless tanning agent. It is from this scientific testing that the potential benefits of PT-141 were discovered. Scientists have determined through rigorous testing on animal test subjects, because of the ability to regulate blood flow restriction and inflammation by PT-141, it very well may be instrumental in managing the onset of hemorrhagic shock and reperfusion injury. What this means is it could potentially reduce, or outright prevent inflammation that may be triggered by a variety of irritants or diseases. This, in turn, could also help reduce any damage that could potentially occur within blood vessels and surrounding tissue. Additional studies have determined PT-141 is a potential remedy for the treatment of sexual dysfunction. Results from early research studies has shown PT-141 does not act on the vascular system like former compounds, but works by activating the melanocortin receptors in the brain.

Selank
Selank is a peptide that has a molecular mass of 751.9 and a molecular formula of C33H57N11O9. It is considered to be a heptapeptide, meaning that it is a peptide chain made up of seven amino acids. Its sequence is Thr-Lys-Pro-Arg-Pro-Gly-Pro. According to scientific study that has been based on animal test subjects, it has been determined that the functional mechanics of Selank gives it the capacity to increase the secretion of serotonin. This neurotransmitter is noted for its ties to mood regulation, and it has also been noted to contain links to sleep and appetite regulation. The presence of the peptide and its ability to cause an uptick in the release of serotonin means that the animal test subject can experience a more efficient means of homeostasis in terms of mood, hunger, and sleep. In addition to inducing a greater metabolic rate of serotonin, it has also been determined that Selank has the capacity to modulate the expression of interleukin 6, a white blood cell-secretion that can act as both a pro-inflammatory cytokine and an anti-inflammatory myokine. This secretion plays a key role in stimulating the immune response during infection and after trauma, particularly during instances of tissue damage leading to inflammation.
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