Aveed (Testosterone Undecanoate): A Newly Approved, Slow Acting Injectable Testosterone

Recently, the US FDA approved injectable testosterone undecanoate (2014). Endo Pharmaceuticals will market it under the brand name Aveed. Testosterone undecanoate has actually been available under the brand name Nebido for over 10 years outside the US. Testosterone undecanoate is very slow acting. The drug provides a sustained release of testosterone into the bloodstream for up to 10 weeks.

In its Phase 3 Study, treatment with AVEED 750 mg maintained T levels in the normal range over 10 week dosing interval.6,14 The figure below illustrates T levels after the third injection. While testosterone undecanoate does not raise levels above normal, testosterone injections of TU still do not mimic physiologic dosing.