Peptide Profiles and Protocols
 

Below are some peptide profiles and dosing guidelines that I acquired from another forum. I found these to be extremely informative and beneficial. I can not take credit for any of the research associated with these profiles. Therefore, I must stress the importance of doing your own research. These protocols and guidelines are strictly for educational purposes. I do not condone the use of illicit substances, nor am I qualified physician to give medical advice. Use at your own risk!

IGF-1LR3 (83AA)
Insulin-Like Growth Factor-1, commonly referred to as IGF-1 is a polypeptide hormone that belongs to the growth factor hormone family. This is a naturally produced hormone in all human beings with production primarily occurring in the liver, and to a degree in the peripheral tissues.

IGF-1 is a highly anabolic hormone that affects numerous areas of the human body. It also shares an important relationship with Human Growth Hormone (HGH), and on a structural basis, is similar to insulin.

IGF-1LR3 Is a slightly modified version of IGF. IGF-1 on its own lasts for only a short period in the body before it is excreted and requires multiple doses per day to maintain appropriate serum levels. IGF-1LR3 has been modified to maintain its integrity and function within the body for up to 24 hours. It is only required to be dosed once per day.

EFFECTS: As with anything else, gains are diet and training dependent. A clean diet with ample amounts of quality proteins will yield dramatic results. A noticeable increase in lean mass, enhanced fat loss, increased nutrient uptake and repartitioning effects and a marked increase in strength.

DOSING GUIDELINES: Typical dosing range is between 50-100mcg per day. Although IGF-1LR3 only requires once per day dosing, user reports indicate better results when splitting the daily dose into two injections, spread 10-12 hours apart. IGF-1LR3 can be administered subcutaneously or intramuscularly. IGF-1LR3 cycles should last between 30-50 days with best effects realized between the 30-45 day mark.

IGF-1 DES (1-3) (3AA)
IGF-1 DES: Also known as DES(1-3)IGF-1, this is what is commonly known as the very fast acting form of IGF-1 and is usually the less-preferred of the two. However, it does possess increased strength and potency (approximately ten times that of the original IGF-1, and five times that of IGF-1 LR3). Unlike IGF-1 LR3, IGF-1 DES possesses a far shorter half-life of approximately 20 – 30 minutes. Because of its faster activity and greater strength/potency, the DES variant of IGF-1 is commonly purported to achieve localized muscle growth in the site it is injected into. Although there is some truth to this, studies have demonstrated that it, like IGF-1 in general, will act systemically once it reaches capillaries and the blood stream.

EFFECTS: As with anything else, gains are diet and training dependent. A clean diet with ample amounts of quality proteins will yield dramatic results. A noticeable increase in lean mass, enhanced fat loss, increased nutrient uptake and repartitioning effects and a marked increase in strength.

DOSING GUIDLEINES: IGF-1 DES is most effectively used in the “Peri-workout” window, meaning before, during and after your workout. It is administered intramuscularly, bi-laterally, in the muscle group to be trained. Daily doses are equivalent to those of IGF-1LR3 between 50-100mcg. A typical dosing schedule for an individual using 75mcg per day would look like this: 25mcg immediately pre-workout, 25mcg at the half-way point of the workout and another 25mcg immediately post workout with a minimum of 75g of fast acting carbs/sugars consumed throughout the workout. IGF-1 DES should be utilized on workout days only and can be effectively used for 8-10 weeks before it is advised to take a 2 week break. IGF-1 DES can also be used in conjunction with PEG-MGF for extreme results, with PEG-MGF utilized on off days.
IGF-1 DES can be utilized on or off cycle as well paired with other peptides for increased effect.

PEG-MGF
PEGYLATED MECHANO-GROWTH FACTOR

PEG-MGF is a variant of IGF-1, which is an insulin like growth factor, and can be used to stimulate myoblasts division and allows for muscle fibers to fuse and mature. It stimulates this division of myoblasts in the body through different receptors. It is a peptide that is responsible for damaged muscle recovery and satellite cell growth. In other words it creates new muscle cells and dramatically increases recovery.

EFFECTS: Increased muscle mass and density, increased fat loss, marked increase in strength and endurance over time, enhanced recovery and dramatically reduced DOMS.

DOSING: PEG-MGF is best utilized post-workout and on recovery days. Doses of 200mcg administered intramuscularly, bi-laterally directly into the muscle groups trained are most common. Dosing of once per day as a post-workout tool should be limited to three days per week. A single 400mcg once a week dose for overall recovery is also a common practice. PEG-MGF is also widely used by athletes to bring up lagging muscle groups and when coupled with IGF-1 the results can be dramatic. IGF-1 would be used pre-workout and PEG-MGF would be administered 10-12 hours later as the two are similar enough to compete for the same receptors. In this case the IGF would win the battle and the MGF would be wasted. Ample time is required for the IGF to go to work and clear to a degree as to allow the PEG-MGF to go to work.
The typical protocol for injection :
Injecting 200-400mcg of PEG-MGF bilaterally, intramuscular in the areas you want to target. It exhibits immediate localized effects and will then circulate systemically within your body binding to tissues that need to be repaired after a workout session or injury.

CJC 1295 W/DAC
CJC 1295 W/DAC is a*synthetically produced peptide*that can dramatically increase your plasma growth hormone levels.

CJC 1295 can increase*IGF-1*levels and GH (growth hormone) levels in humans and in animals. DAC is added to this peptide in order to increase the half-life of CJC-1295. Initially CJC 1295 was developed to treat diseases and medical conditions for patients who had muscle disorders, diseases, and burn victims. CJC 1295 has drawn many individuals like athletes from around the globe for its incredible benefits and minimal side effects to enhance their performance on the field, and in the gym.

EFFECTS: Numerous studies have shown that CJC-1295 builds muscle mass, decreases body fat, and otherwise benefits adult users by improving sleep quality and elevating ones own endogenous levels of HGH.

DOSING GUIDELINES: For best effects, CJC-1295 should be administered three times per week. Dosing ranges vary between 200mcg-300mcg per dose. A typical dosing schedule would be Monday, Wednesday and Friday, dosed in the evening approximately two to three hours after your last meal. CJC-1295 can be dosed subcutaneously or intra-muscularly.
STACKING: CJC-1295 W/DAC is in a family of peptides known as a GHRH (Growth Hormone Releasing Hormone). To reap the optimal benefits of CJC-1295 it is common to stack it with a GHRP (Growth Hormone Releasing Peptide) such as GHRP2 or GHRP6. The two peptide families work synergistically to promote optimal GH secretion, muscle building and fat loss.

HGH Fragment 176-191
HGH Fragment 176-191 is a modified form of amino acids 176-191 at the C-terminal region of the human growth hormone (HGH). Studies have shown that it works by mimicking the way natural HGH regulates fat metabolism but without the adverse effects on insulin sensitivity (blood sugar) or cell proliferation (muscle growth) that is seen with unmodified HGH. Like unmodified GH, the HGH fragment 176-191 stimulates lipolysis (breaking down of fat) and inhibits lipogenesis (the formation of fatty acids and other lipids in the body).

EFFECTS: HGH fragment 176-191 is meant to be 12.5 times stronger than human growth hormone (HGH) for weight loss than standard human growth hormone (HGH). Of particular note is that in studies HGH fragment 176-191 had the ability to increase IGF-1 levels which translates into the fragments ability to give anti-aging and MUSCLE SPARING EFFECTS during periods of caloric restriction such as contest prep or dieting for a special event.

DOSING GUIDELINES: HGH Fragment can be dosed at 500mcg twice per day AM/PM on an empty stomach or three times per day at 300mcg for similar effects. For best effects, one of the daily doses should be administered 30 minutes prior to exercise. HGH Fragment should be administered subcutaneously.
COUPLING: HGH Fragment 176-191 can be stacked with HGH for dramatically increased fat loss effects. A typical coupling dose would be 300mcg of HGH Fragment with 1-1.5iu of HGH three times per day or 500mcg of HGH Fragment and 2iu of HGH twice per day. HGH Fragment can also be combined with Helios and T5 for even more increased effect.

GHRP-2
GHRP-2 is a Growth Hormone Releasing Peptide (GHRP) that does not affect appetite or induce a hunger effect. It is a single chain of six amino acids that can stimulate release of ghrelin or can replace low levels of growth hormone in the body. It is a hormone that can help with fighting anti-aging problems.

EFFECTS: Decreased body fat, increase lean body mass, improved sleep, increase in IGF-1 production, increase in bone density and increase in cellular repair. GHRP-2 injections are beneficial for bodybuilders and athletes seeking to increase muscle mass, shed fat and improve performance.

DOSING GUIDELINES: GHRP-2 should be used around 100mcg-300mcg per injection. GHRP-2 should be used only up to 2-3 times a day.

STACKING: GHRP-2 Can be stacked with a GHRH (Growth Hormone Releasing Hormone) such as CJC-1295 W/DAC, Mod GRF (CJC-1295 no DAC) or Sermorelin for enhanced effects.

GHRP-6
GHRP-6 is a Growth Hormone Releasing Peptide (GHRP) like GHRP-2, but it targets the pituitary to secrete the growth hormone that you have stored. GHRP-6 can increase hunger after injection by increasing the amount of the hormone ghrelin, which is produced in the stomch and signals the feeling of hunger or empty stomch, GHRP-6 not only works in releasing stored growth hormones, but also regulates appetite, promotes fat loss through nutrient repartitioning, builds and repairs muscle tissues and helps in healing damaged tendons.

EFFECTS: GHRP-6 will aid in body fat reduction, appetite, muscle growth and quality of sleep. It is also effective in recovery protocols in healing sports related injures such as minor sprains and tears

DOSING GUIDELINES: GHRP-6 should be dosed at 100mcg 20-30 minutes after each meal up to three times per day.

STACKING: For optimal effects, GHRP-6 should be paired with a GHRH such as CJC 1295 or Sermorelin.

Hexarelin
Hexarelin is a synthetic growth hormone secretagogue. It is derived from GHRP-6 and has effects similar to ghrelin. The primary function of hexarelin is to increase plasma levels of growth hormone and promote the development of lean body mass. Indirectly, hexarelin has been shown to improve cardiac function, lower lipid levels, and protect against the effects of certain chemotherapeutic agents. The peptide is currently under investigation for its ability to mitigate the effects of certain metabolic diseases, such as diabetes.

EFFECTS: Like GHRP-6, hexarelin causes substantial, dose-dependent increases in growth hormone. In fact, hexarelin causes more substantial increases in growth hormone than naturally secreted growth hormone releasing hormone.

DOSING GUIDELINES: Hexarelin is most commonly dosed at 200-300mcg once per week for a duration of no more than six weeks before taking a 2-3 week break. Hexarelin is best used at lower doses and in combination with milder GHRP’s such as GHRP-2 and or Ipamorelin.

RESEARCHERS CAN EXPECT Modest increases in lean body mass, improved sleep, increased fat loss. This peptide is very commonly used in calorie restricted situations to preserve lean muscle such as contest preparation or short term, extreme dieting in preparation for a photo shoot or other special event.

Ipamorelin
Ipamorelin is a penta-peptide hormone, a growth hormone secretagogue and a small molecule ghrelin mimetic. Ipamorelin belongs to the most recent generation of GHRPs and causes significant release of growth hormone. Similar to*GHRP-6*and*GHRP-2, it suppresses somatostatin and increases the stimulation and release of Growth Hormone (GH) from the anterior pituitary. It acts very similarly to GHRP-6 without the increase in appetite.

EFFECTS: Increases in lean body mass, decreased body fat, anti-aging properties (faster recovery), Improved sleep and mood elevation. This peptide is very mild and perfect for researchers new to peptides.

DOSING GUIDELINES: Dosing for Ipamorelin is 200-300mcg two to three times daily. Twelve week cycles are quite normal. Ipamorelin is best when stacked with a GHRH. Cabergoline or Pramipexole should be kept on hand in the event prolactin issues arise as well Aromasin and or Letrozole if estrogenic side effects are experienced. Ipamorelin is administered subcutaneously.

ACE-031
Ace-031, also known as ACVR2B, is a soluble form of activin type IIB receptor, which is an inhibitor of myostatin and other naturally occurring proteins that limit muscle growth.* This compound was genetically developed to bind to myostatin before it can attach to its receptor and halt muscle growth.

EFFECTS: Pronounced increase in lean body mass, increased fat loss, increased bone density.

DOSING GUIDELINES: Initial research used doses of 1-3mg per kilogram of bodyweight, once per month. Common practices however seem to be doses of 1-3mg per month regardless of bodyweight, which, when used as a part of a comprehensive approach utilizing GHRP’s and GHRH’s still yields respectable results at an affordable cost. ACE can be administered subcutaneously or intramuscularly based on individual preference.

Follistatin 344
Follistatin 344 is a protein used in order to increase muscle mass through the suppression of myostatin. Scientists discovered it while they observed the porcine follicular fluid in the ovaries. This protein can be found in the skeletal muscle of humans and other mammals, containing carbohydrates attached to it. Follistatin 344 was the first autocrine glycoprotein supplement to become popular in search of the increased tissue mass

EFFECTS: Pronounced increase in lean body mass. Notable strength increase.

DOSING GUIDELINES: Doses of 100mcg per day for cycles ranging from 10-30 days. Like all myostatin inhibitors, best results are achieved when used in combination with GHRP’s, GHRH’s and Growth Factors such as PEG-MGF, IGF-1 DES and IGF-1LR3. Follistatin can be administered subcutaneously or intramuscularly based on individual preference.

AOD-9604
HGH Fragment 176-191 Evolved
AOD-9604 (Advanced Obesity Drug) also known as Lipotropin is a drug used in obesity treatment. It is a peptide derived from amino acids 176-191 of the GH polypeptide, which enhances fat reducing effects. One of the advantages of this drug is the absence of adverse effects on blood sugar and insulin resistance. AOD-9604 has shown potential effects to repair cartilage and muscle, and it is often used in the treatment of osteoarthritis.

EFFECTS: Enhanced fat burning, increased lean body mass, enhanced recovery and joint health.

DOSING GUIDELINES: Typically dosed in the vicinity of 300mcg at bedtime. This peptide works extremely well when incorporated into a comprehensive weight/fat loss program utilizing stimulatory compounds during waking hours and AOD being administered in the evening to keep lipolysis on-going during sleep. AOD is administered subcutaneously for best effect.

DSIP
DSIP (Delta Sleep-Inducing Peptide) is a neuropeptide that induces sleep. It induces the spindle and delta EEG activity and reduces motor activities. DSIP is classified as an amphiphilic peptide, which represents a chemical compound possessing both hydrophilic and lipophilic properties. This substance has been found in the hypothalamus, limbic system, pituitary and in other organs such tissues and body fluids. This peptide is found abundantly in the gut secretory cells and in the pancreas.

EFFECTS: Creates a general feeling of relaxation and increases ones ability to fall asleep and stay asleep. Deceases cortisol levels, Stimulates the release of luteinizing hormone (LH), Increases the release of Growth Hormone Releasing Hormone(GHRH), Normalizes blood pressure, may improve body composition as a result of decreased cortisol levels.

DOSING GUIDELINES: DSIP is typically dosed between 200-300mcg 30-45 minutes before bed time. Researchers will have to determine their own individual “sweet spot” but it is generally between 200-300mcg.

FTPP (ADIPOTIDE)
FAT TARGETED PROAPOPTIC PEPTIDE
FTPP (Adipotide) is designed to target the specific blood vessels supplying adipose tissue with blood. By denying fat cells an adequate blood supply, FTPP is able to kill fat cells thereby causing a decrease in the volume and mass of subcutaneous fat. Adipotide is able to kill the adipocytes (fat cells) by selectively causing programmed cell death (apoptosis) of the blood vessels supplying the adipocytes.*

EFFECTS: Significant reduction in body fat (most notably in the typical “trouble areas” of both men and women), increased insulin sensitivity.

DOSING GUIDELINES: Research has determined that the most effective dose of this peptide is 43-45mcg per kg of body weight, administered once daily. FTPP is administered subcutaneously.

TB500
TB500 (Thymosin Beta 4) is a muscle recovery drug. It is present in the body and is commonly found in the skeletal muscles and all muscles of the body. Many bodybuilders inject TB-500 into their body to increase the healing process of their naturally occurring TB-500. It has a vital role in building new blood vessels, new small muscle tissue fibers, cell migration and blood cell reproduction. The main focus of using TB-500 is to increase the production of Actin in the body that is associated with muscle repair.

EFFECTS: This peptide speeds injury repair, increases joint mobility and encourages tissue repair. Improved athletic performance and body composition have also been associated with TB500.

DOSING GUIDELINES: Dosing of TB500 consists of two phases. A repair phase where doses of 2-2.5mg are administered subcutaneously twice per week for 4-6 weeks, followed by a maintenance phase of 4-6 months consisting of once monthly doses of 2.5mg.

STACKING: TB-500 can be stacked with BPC-157 for extreme healing abilities

BPC-157
BPC-157 (pentadecapeptide) is an injectable peptide developed for alleviating stomach ulcers. It is characterized by its ability to accelerate the healing of a huge variety of wounds such as skin, cornea, muscle, colon, bone defects and tendons.

EFFECTS: BCP-157 has shown impressive results with regards to healing. Some injuries that take more time to recover are those related to muscles and ligaments. This protein allows faster healing process bringing an excellent advantage to injured athletes to achieve their recovery in less time.

DOSING GUIDELINES: Dosages of 250mcg twice per day have been reported to yield exceptional results.

STACKING: BPC-157: Can be stacked with TB-500 for extreme healing abilities.

PT-141
Libido
PT-141 or Bremelanotide is the generic term for a research peptide being studied for its possible use in helping to improve sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). PT-141 was developed from the tanning peptide*Melanotan 2.

EFFECTS: Improved erectile quality in men and increased vaginal moisture in women. Causes a noticeable increase in arousal in BOTH SEXES. Onset of effects generally occurs about four hours after administration. * may cause slight nausea and flushing of the face, neck and shoulders within 2-3 minutes after administration but symptoms quickly dissipate within a few minutes.

DOSING GUIDELINES: PT-141 is generally dosed between 1mg -2mg approximately four hours prior to sexual activity. PT does require increased dosing with more frequent usage. PT-141 is administered subcutaneously.

Triptorelin
Triptorelin is a GnRH (Gonadotropin Releasing Hormone). GnRH is a chemical that is sent from our brain to the pituitary to tell it to produce both FSH and LH. When a small pulsed dose of GnRH is injected, your pituitary receives that signal to start producing. This will result in both an increase in testosterone serum (as a result from the LH stimulation) and an increase in sperm (or egg in a female case) count. The result may be an effective jumpstart to our reproductive system for steroid users.

EFFECTS: Triptorelin is typically used as a “one shot” alternative to the time tested, 10 day, 1000iu HCG protocol used by AAS users prior to beginning Post Cycle Therapy (PCT). It is also used to kick start the reproductive system in female AAS users after a cycle to restore normal menstrual function and fertility as well as restore virility in males after a particularly suppressive cycle.

DOSING GUIDELINES:1 single 100mcg dose administered subcutaneously after all esters have cleared the body. *If normal pituitary function is not restored after the 100mcg dose, DO NOT, UNDER ANY CIRCUMSTANCES, ADMINISTER ANOTHER DOSE. At doses exceeding 100mcg, pituitary function and FSH/LH production can be permanently and irreversibly damaged (at doses of 1000mcg this drug is used as a chemical castration method through over-stimulation of the pituitary gland) THIS PEPTIDE SHOULD NOT BE USED MORE THAN FOUR TIMES PER YEAR.