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Old 03-09-2012, 06:15 PM
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Default What exactly is hgh? P.III

For a normal cycle of 5-8 months in length, injecting once or twice a day, 7 days a week should be fine. While there are studies that suggest that the suppression and negative feedback from exogenous HGH is short lived (about 4 hours from time of injection), there are no large-scale studies to indicate safety of everyday injections in long-term use. There are studies by anti-aging groups demonstrating that a day or two off per week is adequate to protect the pituitary and its triggers over long cycles. If your use of HGH becomes more a lifestyle than a single cycle, I would consider running it 5 on/2 off, or 6 on/ 1 off until such time as we have reliable data demonstrating long-term safety sans any degradation of your own output or the triggers initiating that output. I have personally experimented with just about every conceivable injection strategy I could devise. What I can say about the anti-aging doctor?s supposition is that it panned out for me. I have recently come off of a 7-year run of HGH. I personally pull my own blood panels every six weeks routinely. After many months of being off of HGH, I now have the same profile I had before I began its use many years ago ? high normal for my age. All levels and markers are perfectly normal.

Another option would be to run your HGH cycle everyday for the first two months to get your IGF-1 levels elevated quickly and to a level to assist you in an anabolic way, then drop back to 5 days a week. If you can tolerate the sides of higher doses, running the same weekly dose divided every other day is fine as well. The list goes on and frankly is an individual proposition. What seems to be of greatest import is that your weekly supplement of HGH is respectable enough to provide the desired benefit.

TIMING
As described above, the body produces HGH is a pulsatile fashion throughout the day with the heaviest pulses occurring approximately 2 hours or so after going to bed and as you fall into a deep sleep. Injectible HGH is completely absorbed and put to use within approximately 3 hours. The strategy with respect to timing depends somewhat on our age and the other elements of our cycle. As you will see below, there is no single best strategy ? it depends a lot on your individual situation.

For those that are between their late 20?s and early 50?s, there is still a reasonable chance that your own endogenous production of HGH is at a reasonable level. The best time to take and injection, this being the case, would be early morning ?. After your body?s own release of HGH in the night. If you get up to go to the bathroom in the early morning (3 -5am), this is probably the perfect time to take a couple of units of HGH. This will be the least disruptive time to take an injection of HGH. The second best time would be first thing in the morning when you wake up.

If you are splitting your doses, the two times of the day when your cortisol levels are at peak are when you wake up and in the early afternoon. This being the case, another good strategy is to take your HGH injections at these times. Cortisol is very catabolic by nature and a well -timed HGH injection can go a long way toward blunting this effect.

If you are in your late 50?s or beyond, or if for some reason you have a condition that has rendered your pituitary incapable of a normal release of HGH, a great time to take HGH is right before bed. This allows you to closely mimic the natural pattern that would occur if your pituitary were functioning properly. For the rest of us, taking your HGH right before bed is going to end up creating a negative feedback loop, robbing you of your body?s own nightly pulse of HGH. While the jury is still out (conflicting studies) as to the absolute nature of the negative feedback time, it is clear that the closer we push our injection to the time our body is ready to give us its biggest pulses of HGH, we are going to end up derailing our own triggers and secretion.

Yet another strategy should be considered if you are using insulin with your HGH. Insulin should be used immediately post workout. HGH and insulin do some great things together ? they shuttle nutrients in a very complimentary way with each other, and the combination of HGH and Insulin create the best environment for IGF-1 production from the liver. If you are using insulin immediately post workout, taking a few IU?s of HGH pre-workout will allow HGH to offer all of its fat mobilizing effects while getting your HGH and Insulin to the liver at about the right time for huge IGF-1 releases.

SIDE EFFECTS ? HOW TO MANAGE THEM

While HGH for the most part is well tolerated, there are some minor, mostly nuisance side effects that can occur. The biggest and most common side effect is bloating and joint pain. The chances of getting these can be minimized or even eliminated by utilizing the ramp up method discussed above in this guide.

If you are younger than your late 20?s, it would be very wise to enter an HGH cycle under the guidance of an MD, who can monitor and confirm whether your growth plates have fused. While abnormal bone growth with HGH use is not common, if used at the wrong point in your body?s development, it could cause disproportionate growth.

If you have a history of cancer or other tumors (at any age), it would be wise to get a complete checkup and be monitored by an MD to make sure that there are no active tumors before your HGH cycle. While HGH (and IGF-1) won?t cause cancer or tumors, they can create an environment that can allow already existing, active tumors to grow at an accelerated rate. We intentionally keep growth factor levels to a minimum in cancer patients. While tumors can create their own growth factors, we really don?t want to throw gas on the fire and allow them to grow any faster than they otherwise could.

Beyond these considerations, there really isn't anything specific that you would HAVE to take with HGH. There are supplements that you could take for specific conditions that are possible with HGH use. The way people react to HGH is a pretty individual thing. Some people get very little suppression of any kind; others don't see any gains from adding HGH because of significant enough suppression of one kind or another. Here's a general rundown of a few of the bigger ones.

For the slight thyroid support that may be desired:
conservative - take nothing
moderate - t-100x, bladderwrack, coleus forskolin, selenium, zinc, chromium, copper
aggressive - T3 at a dose of 12.5 - 25 mcgs or T4 at 100mcgs per day.

For the insulin resistance that is possible:
conservative - 300mg of Alpha Lipoic Acid and 200 - 300mcgs of Chromium Piccinolate
moderate - 15mg of Actos - a prescription med to increase insulin sensitivity, Glucophage (Metformin) to dispose of excess glucose and increase uptake in muscles.
aggressive - add a few IU's of insulin to your HGH cycle

For healthy test levels to best utilize HGH:
conservative - do nothing
moderate - use Tongkat or Tribulus
aggressive - add 200-300 milligrams (or more) of testosterone weekly to your HGH cycle

For protection against prostate growth:
conservative - do nothing
moderate - use Saw Palmetto (approx 2000mg)
aggressive - use Proscar or equivalent

For those that have a problem with breast tissue growth while on HGH:
For those that suffer from this, there is a difference of opinion as to the cause. In the presence of adequate estrogen, HGH can prompt growth of breast tissue. Also of interest is the fact that growth hormone, prolactin, and placental lactogen are a subfamily of a large 2-class cytokine superfamily of proteins. The amino acid sequences of hGH and hPL are similar (85% homology). In humans, each of these three proteins can bind hPRL receptors and promote a variety of physiological actions, including breast growth, lactation, and the like.

The current consensus seems to be that the best approach for those with this problem is twofold - Take 200mg of B6 (or Bromo if B6 is not sufficient) and also use 20-40mg of Tamoxifen (Nolva) to control this. If all else fails, a couple of months of Letro and Bromo will most certainly (and aggressively) deal with the problem. This is a pretty rare condition, but I have talked with more than a few bros that have reported this sort of problem.

Once again, I wouldn't say that all (or any) of these are necessary for everyone. I would use these supplements as necessary to correct whatever conditions arise with your own HGH use. As stated above, reaction to HGH (and just about anything else we use) is very individual.

Hopefully this guide has given you a better understanding of HGH and what it can do for you. HGH, especially when used in conjunction with an AAS cycle, will produce some high-quality, lean mass gains. It can also be used in conjunction with IGF-1 and insulin, which will be the topic of a comparative guide, that I will get posted one of these days.
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